The onset of the first episode of major depressive disorder may not be obvious if it is gradual or mild. The symptoms of this disorder characteristically represent a significant change from how a person functioned before the illness. The symptoms of depression may include:
- feelings of worthlessness, hopelessness, helplessness or guilt
- persistently sad or irritable mood
- pronounced changes in sleep habits and energy levels
- pessimistic feelings about the future
- trouble making decisions
- significant weight gain or loss
- difficulty thinking or concentrating
- low libido
- increased agitation
- lack of interest in or pleasure from activities typically enjoyed
- recurrent thoughts of death and/or suicide
When several of these symptoms occur at the same time, last longer than two weeks, and interfere with ordinary functioning, individuals should seek professional advice and treatment. If left untreated, major depression can lead to attempted suicide.
